FACTORES QUE INFLUYEN EN EL PRONOSTICO DE LA COAGULACION INTRAVASCULAR DISEMINADA EN PACIENTES CON SEPSIS EN EL SERVICIO DE URGENCIAS

Abstract

The disseminated intravascular coagulation it is considered as a complication of the critical illness it is associated with high risk of mortality. Is currently the most widely accepted rating system, proposed by International Society Thrombosis and Hemostasis (ISTH), with which has been found to 25 – 50% of patients with sepsis have CID. The aim of study was measure the association among the factors of risk Disseminated Intravascular coagulation (DIC) and forecast of patients with sepsis. Material and methods. A observational study longitudinal type was performed in a prospective cohort, with diagnosis of sepsis who developed DIC, as the ISTH propose. Analysis includes mean differences of the independent variables by the t-Student, the U of Mann y Withney, and survival analysis, using tables of Kaplan Meier. Results. A total 50 patients were included in the study, the average age was 75.5 years, 56.6% were females. 42% developed DIC, of risk factors with the higher value, 42% presented type 2 Diabetes mellitus, 66% arterial hypertension, and 38% acute renal failure. 74% of population had one site of infection, 22% two site of infection, 64% was associated with an abdominal infection site, and 60% a respiratory infection site. 58% of the population died, of whom 38% DIC development. Conclusion. This study confirms that the DIC has a high frequency in patients that sepsis presenting and is a predictor of mortality by self. It should be the starting point for new clinical studies to better understand this disease, which contribute to early diagnosis and therefore better treatment.